Guanylyl Imidodiphosphate
Catalog No.
C3593
stimulator of adenylate cyclase
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Guanylyl Imidodiphosphate (CAS 148892-91-5) is a small molecule known to stimulate adenylate cyclase activity. Adenylate cyclase catalyzes the production of cyclic AMP, a second messenger involved in diverse cellular signaling pathways. In vitro analysis indicates that microtubules assembled with guanylyl imidodiphosphate closely resemble those polymerized with GTP concerning growth rates, structural arrangement, and stability. However, the dynamics of subunit exchange appear slower compared to GTP-containing microtubules. This compound serves as a useful tool in biochemical studies examining nucleotide-dependent microtubule assembly mechanisms.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 588.1 |
| Cas No. | 148892-91-5 |
| Formula | C10H14N6O13P3·3Na |
| Solubility | ≤10mg/ml in PBS(pH7.2) |
| Chemical Name | monoanhydride with imidodiphosphoric acid, 5'-guanylic acid, trisodium salt |
| SDF | Download SDF |
| Canonical SMILES | O[C@H]1[C@H](N2C=NC3=C2N=C(N)NC3=O)O[C@H](COP(OP(NP(O)([O-])=O)([O-])=O)([O-])=O)[C@H]1O.[Na+].[Na+].[Na+] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
