GNE-781
Catalog No.
BA4661
GNE-781 is a potent, selective inhibitor with oral activity.
Featured Products
GNE-781 is a potent, selective inhibitor with oral activity of 0.94 nM in the TR-FRET assay.GNE-781 displays antitumor activity in the MOLM-16AML xenograft model.
| Physical Appearance | A solid |
| Storage | -20°C |
| M.Wt | 525.59 |
| Cas No. | 1936422-33-1 |
| Formula | C27H33F2N7O2 |
| Solubility | ≥51.1 mg/mL in DMSO; ≥45.9 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | 3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide |
| Canonical SMILES | FC(F)C1=CC2=C(CCCN2C3=NN(C4CCOCC4)C5=C3CN(C(NC)=O)CC5)C=C1C6=CN(C)N=C6 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
