Fmoc-D-2-Me-Trp
Fmoc-D-2-Me-Trp (CAS: 196808-79-4) is an Fmoc-protected D-form methylated tryptophan derivative frequently utilized as an amino acid building block in peptide synthesis and structural modifications. Its methyl substitution at the side chain serves to modulate peptide conformation, thereby influencing binding interactions between peptide ligands and protein receptors. By altering ligand-protein interface specificity and stability, this compound facilitates investigation into protein-ligand recognition mechanisms, making it valuable in peptide-based pharmacological and medicinal chemistry research.
| Storage | Store at -20°C |
| M.Wt | 440.49 |
| Cas No. | 196808-79-4 |
| Formula | C27H24N2O4 |
| Solubility | insoluble in H2O; ≥2.65 mg/mL in EtOH with gentle warming and ultrasonic; ≥57.1 mg/mL in DMSO |
| Chemical Name | (R,E)-2-((((9H-fluoren-9-yl)methoxy)(hydroxy)methylene)amino)-3-(2-methyl-1H-indol-3-yl)propanoic acid |
| SDF | Download SDF |
| Canonical SMILES | Cc1c(C[C@H](C(O)=O)/N=C(\O)/OCC2c(cccc3)c3-c3c2cccc3)c(cccc2)c2[nH]1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure








