Ferulenol
Catalog No.
C3889
antimycobacterial activity and stimulates tubulin polymerization
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Ferulenol (CAS 6805-34-1) is a prenylated derivative of 4-hydroxycoumarin extracted from Ferula communis var. genuina. It functions by interacting with tubulin to promote polymerization independently of GTP and competitively reduces colchicine binding. Studies have demonstrated significant antimicrobial effects, particularly antimycobacterial activity. In vitro, ferulenol induces abnormal nuclear morphology and dose-dependently decreases viability of MCF-7 cancer cells. In animal models, acute exposure to ferulenol caused marked hypoprothrombinemia and hemorrhagic toxicity. Thus, ferulenol serves as a valuable molecular probe in research on tubulin dynamics, cancer biology, and microbial inhibition.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 366.5 |
| Cas No. | 6805-34-1 |
| Formula | C24H30O3 |
| Solubility | Soluble in DMSO |
| Chemical Name | 4-hydroxy-3-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]-2H-1-benzopyran-2-one |
| SDF | Download SDF |
| Canonical SMILES | O=C1C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)=C(O)C2=CC=CC=C2O1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
