Felypressin Acetate

Felypressin Acetate (CAS No.: 56-59-7) is a synthetic peptide vasoactive research compound and a vasopressin related non catecholamine vasoconstrictor analog, commonly categorized in cardiovascular and smooth muscle pharmacology as a vasopressin receptor agonist with primary activity at V1 type signaling systems that regulate vascular tone through G protein coupled phospholipase C activation, inositol phosphate turnover, intracellular calcium mobilization, and contraction of vascular smooth muscle; relative to endogenous vasopressin like peptides it is generally described as retaining vasoconstrictive pharmacology with comparatively reduced antidiuretic bias, and is therefore used in mechanistic studies of receptor selectivity, peptide agonist structure activity relationships, and tissue specific contractile responses in isolated vessel preparations, receptor expressing cell based assays, and translational animal pharmacology models of hemodynamic regulation, while published quantitative potency values are context dependent and should be interpreted from assay specific literature, with reported peptide agonist testing in this class commonly spanning nanomolar to micromolar concentration ranges depending on receptor system, species background, and readout platform; in discovery workflows it is frequently applied as a reference agonist or comparator in screening programs focused on vasoactive pathways, GPCR signaling modulation, and peptide lead optimization, and the concentrations or doses used in experiments typically depend on specific experimental designs and research objectives.