Estramustine
Catalog No.
BA4256
Estramustine is an antitumor agent.
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Estramustine is an antitumor agent. Estramustine depolymerizes microtubules and has antimitotic activity, with an approximate mitotic IC50 of 16 μM in DU145 cells. Estramustine blocks mitosis of prostate tumor cells in a prostate tumor xenograft model.
| Physical Appearance | A solid |
| Storage | 4°C, protect from light |
| M.Wt | 440.40 |
| Cas No. | 2998-57-4 |
| Formula | C23H31Cl2NO3 |
| Solubility | ≥46.6 mg/mL in DMSO; ≥23.85 mg/mL in EtOH; insoluble in H2O |
| Chemical Name | (8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl bis(2-chloroethyl)carbamate |
| Canonical SMILES | C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC(N(CCCl)CCCl)=O)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H] |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
