ERRα antagonist-1
Catalog No.
A9977
A selective, high-affinity antagonist of estrogen-related receptor alpha (ERRα)
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ERRα antagonist-1 (Compound A) is a selective, high-affinity antagonist of estrogen-related receptor alpha (ERRα). ERRα is a member of the nuclear receptor superfamily and is structurally similar to the estrogen receptor (ER) but does not bind to natural estrogens. Compound A can specifically bind to ERRα and inhibit its transcriptional activity, thereby regulating ERRα-mediated gene expression, and thereby affecting cell metabolism, energy homeostasis, and tumor cell proliferation and migration. The compound has potential pharmacological applications in metabolic diseases, cancer therapy and other fields.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 377.52 |
| Cas No. | 1072145-33-5 |
| Formula | C21H19N3S2 |
| Solubility | Soluble in DMSO |
| Chemical Name | (Z)-N-(5H-dibenzo[a,d][7]annulen-5-yl)-3-(4,5-dihydrothiazol-2-yl)thiazolidin-2-imine |
| SDF | Download SDF |
| Canonical SMILES | C12=CC=CC=C1C(/N=C3SCCN\3C4=NCCS4)C5=CC=CC=C5C=C2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
