Davunetide

Davunetide is an eight-amino acid peptide derived from activity-dependent neuroprotective protein (ADNP), a neurotrophic factor found in the mammalian central nervous system.Davunetide has neuroprotective, neurotrophic, and cognitive protective properties.Davunetide is a microtubule-stabilizing peptide that interacts with and stabilizes the activity of neuron specific βIII microtubule protein in vitro.Davunetide crosses the blood-brain barrier and is non-toxic.Davunetide inhibits Aβ aggregation and Aβ-induced neurotoxicity. Davunetide is a microtubule-stabilizing peptide that interacts with and stabilizes neuron-specific βIII microtubule proteins in vitro.Davunetide crosses the blood-brain barrier and is non-toxic.Davunetide inhibits Aβ aggregation and Aβ-induced neurotoxicity.