cyclo(RLsKDK) TFA
Catalog No.
A9930
An inhibitor of metalloprotease ADAM8
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Cyclo(RLsKDK) TFA is a cyclic pentapeptidase that commonly acts as an inhibitor of metalloprotease ADAM8. ADAM8 is a transmembrane protein that exhibits abnormal expression and activity in a variety of pathological states, such as inflammation, cancer, and neurodegenerative diseases. cyclo(RLsKDK) (TFA) specifically inhibits ADAM8 and has potential applications in the treatment of inflammatory diseases and cancer.
| Storage | Store at -20°C away from light for 3 years. |
| M.Wt | 841.89 |
| Formula | C33H58F3N11O11 |
| Solubility | ≥55.8 mg/mL in DMSO; ≥19.73 mg/mL in EtOH; ≥18.23 mg/mL in H2O |
| Chemical Name | 2,2,2-trifluoroacetic acid--2-((2S,5S,8S,11S,14R,17S)-5,17-bis(4-aminobutyl)-8-(3-guanidinopropyl)-14-(hydroxymethyl)-11-isobutyl-3,6,9,12,15,18-hexaoxo-1,4,7,10,13,16-hexaazacyclooctadecan-2-yl)acetic acid (1/1) |
| SDF | Download SDF |
| Canonical SMILES | O=C(O)C[C@H](NC([C@H](CCCCN)NC([C@@H](CO)NC([C@H](CC(C)C)NC1=O)=O)=O)=O)C(N[C@@H](CCCCN)C(N[C@H]1CCCNC(N)=N)=O)=O.OC(C(F)(F)F)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
