Cyclic-di-GMP disodium
Catalog No.
C8584
An important STING agonist and also a bacterial second messenger
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Cyclic-di-GMP disodium is an important STING agonist and also a bacterial second messenger. It plays a key role in bacteria, coordinating multiple aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Studies have found that Cyclic-di-GMP disodium has significant anti-cancer cell proliferation activity. It can induce an increase in CD4 receptor expression in cancer cells and cause cell cycle arrest, thereby inhibiting the growth and spread of cancer cells.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 734.38 |
| Cas No. | 2222132-40-1 |
| Formula | C20H22N10Na2O14P2 |
| Solubility | Soluble in DMSO |
| Chemical Name | sodium (2R,3R,3aS,7aR,9R,10R,10aS,14aR)-2,9-bis(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3,10-dihydroxyoctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9]tetraoxa[2,8]diphosphacyclododecine-5,12-bis(olate) 5,12-dioxide |
| SDF | Download SDF |
| Canonical SMILES | O=C1NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](COP(O4)(O[Na])=O)[C@@H](OP(OC[C@@H]5[C@@H]4[C@@H](O)[C@H](N6C=NC7=C6N=C(N)NC7=O)O5)(O[Na])=O)[C@H]3O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
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Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
