Crotaline
Catalog No.
N1470
A pyrrolizidine alkaloid with antitumor activity, commonly used to construct pulmonary arterial hypertension (right ventricular hypertrophy) animal models.
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Monocrotaline (CAS 315-22-0) is a pyrrolizidine alkaloid extracted from Crotalaria assamica (family Fabaceae) with antitumor activity. Suitable solvents are methanol, ethanol, and chloroform, and the product should be sealed and stored in a cool, dry place.
A single injection of monocrotaline damages pulmonary vessels and causes right ventricular hypertrophy, and it is commonly used to establish pulmonary hypertension (right ventricular hypertrophy) animal models.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 325.36 |
| Cas No. | 315-22-0 |
| Formula | C16H23NO6 |
| Synonyms | Monocrotaline |
| Solubility | ≥1.66 mg/mL in H2O with gentle warming and ultrasonic; ≥16.45 mg/mL in ETOH with gentle warming and ultrasonic; ≥67.2 mg/mL in DMSO |
| Chemical Name | (3R,4R,5R,8a1R,13aR)-4,5-dihydroxy-3,4,5-trimethyl-4,5,8,8a1,10,12,13,13a-octahydro-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione |
| Canonical SMILES | C[C@H]([C@](C)([C@](C)(C(OCC1=CCN(CC2)[C@H]1[C@@H]2O1)=O)O)O)C1=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
