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COH34

Catalog No.
BA4421
COH34 is a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase.
Grouped product items
SizePriceStock Qty
1mg
$112.00
In stock
5mg
$315.00
In stock
10mg
$481.00
In stock
25mg
$770.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

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Background

COH34 is a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase with a value of 0.37 nM.COH34 binds to the catalytic structural domain of PARG (=0.547 μM), thereby prolonging PARylation at the site of DNA damage and capturing the DNA repair factor.

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt293.38
Cas No.906439-72-3
FormulaC18H15NOS
Solubility≥17.05 mg/mL in DMSO with ultrasonic; ≥3.96 mg/mL in EtOH with ultrasonic; insoluble in H2O
Chemical Name(E)-1-(((p-tolylthio)imino)methyl)naphthalen-2-ol
SDFDownload SDF
Canonical SMILESCC1=CC=C(S/N=C/C2=C(C=CC=C3)C3=CC=C2O)C=C1
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

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