Choline theophyllinate

Oxtriphylline (CAS No.: 4499-40-5) is a xanthine derivative prepared as the choline salt of theophylline and is broadly categorized as a small molecule phosphodiesterase modulator used in biochemical and pharmacological research focused on airway biology, inflammation associated signaling, and cyclic nucleotide regulation, with a mechanistic profile primarily linked to non selective phosphodiesterase inhibition and consequent elevation of intracellular cyclic AMP, alongside reported adenosine receptor antagonistic activity that is commonly discussed for methylxanthine class compounds, thereby supporting pathway level investigation of cAMP dependent signaling networks, smooth muscle tone regulation, and immune cell responsiveness in preclinical systems; based on class associated evidence, its in vitro functional activity is generally described in the micromolar to high micromolar range depending on assay format, enzyme subtype, and cellular context, and it is therefore typically applied as a reference or comparator tool compound in cell based studies of bronchial or immune relevant phenotypes, in mechanistic assays of phosphodiesterase linked signal transduction, and in exploratory animal pharmacology models where concentration or dose selection is determined by specific experimental design, exposure conditions, and study objectives in drug discovery workflows.