(-)-Catechin
(-)-Catechin (CAS 18829-70-4) is one of the non-enantiomeric isomers of catechin (CAS 154-23-4), with a chiral center exhibiting a 2S,3R trans configuration.
Catechin (Catalog No. A4629) is a polyphenolic flavonoid compound that can be isolated from various natural sources, including tea leaves, grape seeds, as well as the wood and bark of trees such as acacia and mahogany. This compound is a potent antioxidant, capable of inhibiting the free radical oxidation of low-density lipoprotein (LDL) isolates induced by AAPH (Catalog No. C5140).
In a two-stage mouse skin cancer model, catechin and other related proanthocyanidin compounds have demonstrated significant antitumor activity when applied topically.
References:
[1] Antioxidant activity of resveratrol and alcohol-free wine polyphenols related to LDL oxidation and polyunsaturated fatty acids
[2] Zhao J, Wang J, Chen Y, Agarwal R. Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. Carcinogenesis. 1999 Sep;20(9):1737-45. doi: 10.1093/carcin/20.9.1737. PMID: 10469619.
| Storage | Store at -20°C |
| M.Wt | 290.27 |
| Cas No. | 18829-70-4 |
| Formula | C15H14O6 |
| Synonyms | (-)-Cianidanol; (-)-Catechuic acid |
| Chemical Name | (2S,3R)-2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol |
| SDF | Download SDF |
| Canonical SMILES | O[C@@H]1CC2=C(O)C=C(O)C=C2O[C@H]1C3=CC=C(O)C(O)=C3 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
