Bufuralol (hydrochloride)
Catalog No.
C5043
non-specific β-adrenergic blocker
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Bufuralol hydrochloride (CAS 60398-91-6) is a small molecule functioning primarily as a non-selective β-adrenergic receptor antagonist. It interacts broadly with beta-adrenoceptors and demonstrates partial intrinsic sympathomimetic activity, as evidenced by its induction of tachycardia in animal models with depleted catecholamine stores. In vitro analyses indicate that bufuralol additionally exhibits membrane-stabilizing effects. Clinically, bufuralol has shown prolonged inhibitory action on exercise-induced heart rate elevation comparable to propranolol, suggesting utility in research investigating β-adrenergic modulation and cardiovascular pharmacology.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 297.8 |
| Cas No. | 60398-91-6 |
| Formula | C16H23NO2·HCl |
| Synonyms | Ro 3-4787 |
| Solubility | ≤15mg/ml in ethanol;10mg/ml in DMSO;15mg/ml in dimethyl formamide |
| Chemical Name | α-[[(1,1-dimethylethyl)amino]methyl]-7-ethyl-2-benzofuranmethanol, monohydrochloride |
| SDF | Download SDF |
| Canonical SMILES | CCC1=C(OC(C(O)CNC(C)(C)C)=C2)C2=CC=C1.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Purity ≥ 95.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
