BTM-3528
Catalog No.
BA3193
BTM-3528 is an activator of the mitochondrial protease OMA1 and mediates hyperactivation of the mitochondrial integrative stress response (ISR).
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BTM-3528 is an activator of the mitochondrial protease OMA1 and mediates overactivation of the mitochondrial integrative stress response (ISR).BTM-3528 stimulates OMA1-dependent DELE1 and OPA1 cleavage, and mitochondrial breakage.BTM-3528 activates the eIF2α kinase HRI, which induces cell growth arrest and apoptosis (cell death). BTM-3528 has anticancer activity against a variety of DLBCL cell lines and has in vivo inhibitory potency in a mouse model of xenografted human DLBCLSU-DHL-10 cells.
Storage | -20°C |
M.Wt | 521.55 |
Cas No. | 2054998-45-5 |
Formula | C24H19F4N3O2S2 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |