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BTM-3528

Catalog No.
BA3193
BTM-3528 is an activator of the mitochondrial protease OMA1 and mediates hyperactivation of the mitochondrial integrative stress response (ISR).
Grouped product items
SizePriceStock Qty
1mg
$288.00
Ship with 10-15 days
5mg
$720.00
Ship with 10-15 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

BTM-3528 is an activator of the mitochondrial protease OMA1 and mediates overactivation of the mitochondrial integrative stress response (ISR).BTM-3528 stimulates OMA1-dependent DELE1 and OPA1 cleavage, and mitochondrial breakage.BTM-3528 activates the eIF2α kinase HRI, which induces cell growth arrest and apoptosis (cell death). BTM-3528 has anticancer activity against a variety of DLBCL cell lines and has in vivo inhibitory potency in a mouse model of xenografted human DLBCLSU-DHL-10 cells.

Chemical Properties

Storage-20°C
M.Wt521.55
Cas No.2054998-45-5
FormulaC24H19F4N3O2S2
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.