Boc-L-Tyrosine methyl ester

Boc-L-Tyrosine Methyl Ester (CAS No. 4326-36-7), a protected L-tyrosine derivative with a tert-butoxycarbonyl (Boc) group on the amino moiety and a methyl ester on the carboxylic acid group (while retaining the phenolic hydroxyl group for further modification), serves as a critical synthetic building block in biochemistry and pharmacology. Its core applications include acting as a fundamental component for both solid-phase and solution-phase peptide synthesis to precisely incorporate tyrosine residues into therapeutic peptides, functioning as an intermediate in drug development—particularly for agents targeting neurological disorders due to structural similarity to neurotransmitter precursors like L-DOPA—enabling bioconjugation, biomolecule immobilization, and protein labeling to track cellular interactions, and supporting cancer research by facilitating the development of targeted therapies and inducing specific enzymatic activities (e.g., matrix metalloproteinase activity) in research models. Notably, Boc-Tyr-OMe does not directly interact with biological targets as a bioactive molecule; instead, its value lies in providing a structurally stable and modifiable scaffold, whose derivatives or peptide-incorporated products mediate targeted biological effects through relevant pathways.