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Bioactive Compounds

Bioactive Compounds

A4651 Defactinib hydrochloride

≥15.75 mg/mL
BA2321 Mertansine

Summary: Mertansine (DM1) is an inhibitor and an antibody-conjugatable medetomidine alkaloid used to overcome the systemic toxicity associated with medetomidine and to enhance tumor-specific delivery.

≥26.65 mg/mL
BA3586 CCT020312

Summary: CCT020312 is a selective activator.
A4203 Tenovin-1

Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21

Summary: SIRT2 inhibitor, activates p53

insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
A4167 SGC 0946

Summary: DOT1L inhibitor,highly potent and selective

≥30.95 mg/mL
A4199 Sabutoclax
2 Citation

Target: Bcl-2|Mcl-1|Bfl-1

Summary: pan-Bcl-2 inhibitor

insoluble in H2O; ≥205.6 mg/mL
A4300 GW9662
7 Citation

Summary: PPARγ antagonist

insoluble in H2O; ≥13.75 mg/mL
A4317 Apremilast (CC-10004)

Target: Phosphodiesterases (PDEs)

Summary: PDE4 inhibitor

≥23.05 mg/mL
A4326 TAK-700 (Orteronel)
3 Citation

Target: human lyase

Summary: Human 17,20-lyase inhibitor

insoluble in H2O; ≥11.2 mg/mL
A4342 Gimeracil

Summary: Dihydropyrimidine dehydrogenase inhibitor