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Bioactive Compounds

Bioactive Compounds

A4084 Vorinostat (SAHA, MK0683)
22 Citation

Target: Histone Deacetylases (HDACs)

Summary: HDAC inhibitor

insoluble in EtOH; insoluble in H2O; ≥4.41 mg/mL
A4060 Geldanamycin
2 Citation

Summary: Hsp90 inhibitor,potent and specific

insoluble in EtOH; insoluble in H2O; ≥16.9 mg/mL
A4154 Olaparib (AZD2281, Ku-0059436)
30 Citation

Summary: PARP-1/2 inhibitor

≥21.72 mg/mL
A4112 Barasertib (AZD1152-HQPA)
6 Citation

Target: Aurora Kinases

Summary: Aurora Kinase B inhibitor, Potent and selective

≥25.4 mg/mL
A4036 Sitagliptin phosphate monohydrate
10 Citation

Target: DPP-4

Summary: Potent DPP-4 inhibitor

≥23.8 mg/mL
A4230 NSC 66811

Summary: MDM2 inhibitor

≥34 mg/mL
A4203 Tenovin-1

Target: Sir2-like Family Deacetylases (Sirtuins)|p53|p21

Summary: SIRT2 inhibitor, activates p53

insoluble in H2O; insoluble in EtOH; ≥15 mg/mL
A4167 SGC 0946

Summary: DOT1L inhibitor,highly potent and selective

≥30.95 mg/mL
A4199 Sabutoclax
2 Citation

Target: Bcl-2|Mcl-1|Bfl-1

Summary: pan-Bcl-2 inhibitor

insoluble in H2O; ≥205.6 mg/mL
A4300 GW9662
7 Citation

Summary: PPARγ antagonist

insoluble in H2O; ≥13.75 mg/mL