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Bioactive Compounds

Bioactive Compounds

A4116 Danusertib (PHA-739358)
2 Citation

Target: Aurora Kinases

Summary: Pan-aurora kinase inhibitor

≥23.75 mg/mL
A4210 Bay 11-7821 (BAY 11-7082)
1 Citation

Summary: IKK/NF-κB/TNFα inhibitor

insoluble in H2O; ≥64 mg/mL
A4216 Thalidomide

Target: Ubiquitin E3 Ligases

Summary: Immunomodulatory agent,sedative drug,angiogenesis inhibitor

insoluble in H2O; insoluble in EtOH; ≥11.8 mg/mL
A4228 Nutlin-3

Target: MDM2

Summary: MDM2 antagonist,inhibits MDM2-p53 interaction

≥58.2 mg/mL
A2614 Bortezomib (PS-341)
52 Citation

Target: Proteasome

Summary: proteasome inhibitor

insoluble in EtOH; insoluble in H2O; ≥19.21 mg/mL
A4304 Rosiglitazone
5 Citation

Summary: Potent PPARγ agonist

insoluble in EtOH; insoluble in H2O; ≥17.85 mg/mL
A4325 PF-2545920

Target: Phosphodiesterases (PDEs)

Summary: PDE10A inhibitor,potent and selective

insoluble in H2O; ≥19.35 mg/mL
A4393 Paclitaxel (Taxol)
28 Citation

Target: Microtubules/Tubulins

Summary: microtubule depolymerization inhibitor

≥85.6 mg/mL
A1930 M50054

Summary: Associate with caspase-3 inhibition
A1932 (-)-Huperzine A

Target: NMDA Receptors|AChE

Summary: NMDA receptor antagonist/AChE inhibitor

insoluble in H2O; ≥12.12 mg/mL