Faropenem daloxate
| Storage | Store at -20°C |
| M.Wt | 397.41 |
| Cas No. | 141702-36-5 |
| Formula | C17H19NO8S |
| Synonyms | Faropenem medoxil |
| Solubility | Soluble in DMSO |
| Chemical Name | (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate |
| SDF | Download SDF |
| Canonical SMILES | CC1=C(OC(=O)O1)COC(=O)C2=C(SC3N2C(=O)C3C(C)O)C4CCCO4 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
| Animal experiment [1]: | |
|
Animal models |
Neonatal/juvenile dogs |
|
Dosage form |
0, 100, 300, 600, and 1400 mg/kg once a day for 4 days |
|
Application |
Evaluation of weight, food consumption, clinical observation, clinical pathology, urine alysis and TK were performed. The research indicated that faropenem daloxate was harmful to to body weight and kidneys at a concentration of 1400 mg/kg. Compared to adult dogs, puppies are more sensitive to Faropenem daloxate kidney toxicity. |
|
Other notes |
Please test the solubility of all compounds indoor, and the actual solubility may slightly differ with the theoretical value. This is caused by an experimental system error and it is normal. |
|
References: [1]. Faqi AS, Lanphear C, Gill S, Colagiovanni DB. Juvenile toxicity study of faropenem medoxomil in beagle puppies. Reprod Toxicol. 2010 Dec;30(4):619-24. doi: 10.1016/j.reprotox.2010.07.010. Epub 2010 Aug 11. PMID: 20708074. |
|
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
