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Bioactive Compounds

Bioactive Compounds

A4309 GW501516
1 Citation

Summary: PPARδ agonist,selective and potent

insoluble in H2O; ≥18.05 mg/mL
A4331 GSK256066

Summary: PDE4-inhibitor, selective and highly potent

insoluble in DMSO; insoluble in EtOH; insoluble in H2O
A4385 Ganetespib (STA-9090)
3 Citation

Summary: Hsp90 inhibitor,non-geldanamycin

insoluble in H2O; ≥18.22 mg/mL
A3191 Ascomycin(FK 520)

Target: phosphatases

Summary: Macrolide immunosuppressant,FK-520 analog

≥38.9 mg/mL
A3433 Gefitinib hydrochloride

Target: EGFR

Summary: Potent EGFR inhibitor

insoluble in EtOH; ≥4.28 mg/mL
A3443 Granisetron

Summary: Serotonin 5-HT3 receptor antagonist

≥25.1 mg/mL
A3634 MPTP hydrochloride

Summary: Dopaminergic neurotoxin,induced reduction in the DOPAC HVA/dopamine (DA) ratio

≥21 mg/mL
A3674 NVP-BKM120 Hydrochloride

Summary: PI3K inhibitor

≥44.7 mg/mL
A3676 NVP-LCQ195

Summary: CDK1/CDK2/CDK5 inhibitor

insoluble in H2O; ≥152.4 mg/mL
A3846 SU14813 maleate

Summary: VEGFR/PDGFR/Kit/FLT-3 inhibitor

Soluble in DMSO