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Bioactive Compounds

Bioactive Compounds

B5378 Conantokin-T

Summary: Non-competitive NMDA receptor antagonist
B5476 Hemopressin (human, mouse)

Summary: CB1 receptor inverse agonist; endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE

Soluble to 1 mg/mL
B5699 P11

Summary: antagonist of the integrin αvβ3-vitronectin interaction
A4137 AZD1480

Target: JAK

Summary: JAK2 inhibitor,ATP-competitive and novel

insoluble in H2O; ≥93.8 mg/mL
A4164 AZD2461

Target: PARP

Summary: Novel PARP inhibitor

insoluble in H2O; ≥16.35 mg/mL
A4032 VX-222 (VCH-222, Lomibuvir)

Target: HCV polymerase

Summary: NNI of HCV RNA polymerase

≥44.6 mg/mL
A4096 Belinostat (PXD101)
2 Citation

Target: Histone Deacetylases (HDACs)

Summary: Hydroxamate-type HDAC inhibitor

insoluble in H2O; ≥15.92 mg/mL
A8201 Amprenavir (agenerase)

Summary: HIV-1 protease inhibitor
A4120 MK-5108 (VX-689)

Summary: Aurora-A kinase inhibitor,highly selective

≥23.1 mg/mL
A4010 Salinosporamide A (NPI-0052, Marizomib)

Target: Proteasome

Summary: 20S proteasome inhibitor

Soluble in DMSO