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Bioactive Compounds

Bioactive Compounds

A1877 XAV-939
16 Citation

Target: TNKS

Summary: Tankyrase 1/2 (TNKS) inhibitor

insoluble in H2O; insoluble in EtOH; ≥15.62 mg/mL
A8361 AMG-458

Summary: Potent c-Met inhibitor

Soluble in DMSO
A8545 ZM336372

Summary: C-Raf inhibitor, potent and selective

insoluble in EtOH; insoluble in H2O; ≥19.45 mg/mL
A8556 GSK2126458
1 Citation

Target: PI3K|mTOR

Summary: PI3K/mTOR inhibitor

≥25.3 mg/mL
A8617 CCT128930 HCl

Target: Akt

Summary: AKT inhibitor

insoluble in H2O; ≥17.1 mg/mL
A8628 Chloroquine diphosphate
16 Citation

Target: Autophagy

Summary: Antimalarial drug, TLR7 and TLR9 inhibitor

insoluble in DMSO; insoluble in EtOH; ≥106.06 mg/mL
A8659 SANT-1
2 Citation

Summary: Shh inhibitor,potent and cell-permeable

insoluble in H2O; insoluble in EtOH; ≥18.75 mg/mL
B3041 BTB06584

Target: F1 Fo-ATPase

Summary: F1F0 ATP synthases

≥17.05 mg/mL
B1402 GZD824

Target: Bcr-Abl

Summary: Bcr-Abl inhibitor,novel orally bioavailable

≥36.25 mg/mL
B1499 RVX-208
2 Citation

Summary: Potent BET bromodomain inhibitor

insoluble in H2O; ≥18.52 mg/mL