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Anti-Inflammatory Peptide 1

Catalog No.
A1008
PLA2 inhibitor
Grouped product items
SizePriceStock Qty
5mg
$60.00
In stock
10mg
$100.00
In stock
25mg
$140.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Anti-Inflammatory Peptide 1 (C45H82N12O14S2), with the sequence H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I. The name 'antiflammins' is proposed for those peptides, which are valuable models for the development of novel anti-inflammatory agents of therapeutic importance. Anti-inflammatory peptide 1 possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites.

A1008_1

Ref:

1. Argiolas A, Pisano JJ (November 1983). "Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom". J. Biol. Chem. 258 (22): 13697–702.

Chemical Properties

Physical AppearanceA solid
StorageStore at -20°C
M.Wt1079.33
Cas No.118850-71-8
FormulaC45H82N12O14S2
SynonymsH2N-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH
Solubility≥107.9mg/mL in DMSO
Chemical NameAnti-Inflammatory Peptide 1
SDFDownload SDF
Canonical SMILESCC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)N
Shipping ConditionEvaluation sample solution: ship with blue ice. All other available sizes: ship with RT, or blue ice upon request.
General tipsFor obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20°C for several months.

Quality Control

Chemical structure

Anti-Inflammatory Peptide 1