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Bioactive Compounds

Bioactive Compounds

B1931 Dimethyl Fumarate

Summary: nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator
B1225 Posaconazole hydrate

Summary: C14ɑ demethylase inhibitor

Soluble in DMSO
B1463 KPT-276

Target: nuclear export|CRM1

Summary: inhibitor of nuclear export (SINE) and CRM1, orally bioavailable

insoluble in EtOH; insoluble in H2O; ≥19.85 mg/mL
B1180 S1RA hydrochloride

Summary: σ1R antagonist

Soluble in DMSO
B1528 XL335

Target: Farnesoid X receptors (FXRs)

Summary: FXR agonist

insoluble in H2O; insoluble in EtOH; ≥20.4 mg/mL
B1423 Cinacalcet HCl

Summary: Calcium-sensing receptor (CaR) agonist

insoluble in H2O; ≥17.85 mg/mL
B1036 MLN4924

39 Citation

Target: NAE|Ubiquitin-activating Enzyme E1|SUMOylation

Summary: NAE inhibitor

≥22.18 mg/mL
B2154 Alprostadil

Summary: vasodilator

insoluble in H2O; ≥13.4 mg/mL
B1184 Milnacipran

Summary: Serotonin-norepinephrine reuptake inhibitor (SNRI)

Soluble in DMSO
B1572 Latrepirdine

Target: Voltage-gated Calcium Channels (CaV)|NMDA receptor|adrenergic receptor|Histamine receptors|GluR|5-HT receptor|dopamine receptors|AMPA receptor

Summary: Brain cell death inhibitor

insoluble in H2O; ≥19.62 mg/mL