Benproperine phosphate

Benproperine phosphate (CAS No.: 19428-14-9) is a synthetic small molecule and phosphate salt form of benproperine that is primarily classified as a bioactive research compound for cytoskeleton biology and cancer cell motility studies, with reported activity as an inhibitor of actin related protein 2 over 3 complex subunit 2 that functionally attenuates Arp2 over 3 complex mediated actin nucleation and reduces actin polymerization dynamics, thereby modulating pathways that govern lamellipodia formation, cytoskeletal remodeling, and migration associated signaling programs in invasive cell phenotypes; within biomedical research workflows it is commonly positioned as a tool compound for mechanistic interrogation of ARPC2 dependent processes, including in vitro assays of cell migration, invasion, and metastatic behavior, as well as exploratory pharmacology and phenotypic screening where activity is generally discussed in the nanomolar to micromolar range or at low micromolar levels depending on assay configuration, while model specific exposure conditions vary across cell based and animal based experimental systems and the concentrations or doses used in experiments typically depend on specific experimental designs and research objectives, and current use should be restricted to controlled laboratory research contexts focused on target validation, pathway dissection, and early stage drug discovery enabling studies rather than any non research application.