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Bafetinib

Catalog No.
BA2759
Bafetinib is an orally active tyrosine kinase inhibitor.
Grouped product items
SizePriceStock Qty
1mL(10 mM in DMSO)
$85.00
In stock
5mg
$67.00
In stock
10mg
$93.00
In stock
50mg
$180.00
In stock
100mg
$324.00
In stock
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Bafetinib is an orally active tyrosine kinase inhibitor.Bafetinib potentiates the activity of several pro-apoptotic homologous (BH)3-pure proteins (Bim, Bad, Bmf, and Bik) through the family-regulated intrinsic apoptotic pathway and induces apoptosis in Ph leukemia cells.Bafetinib has antitumor activity.

Product Citation

Chemical Properties

Physical AppearanceA solid
Storage-20°C
M.Wt576.62
Cas No.859212-16-1
FormulaC30H31F3N8O
SynonymsINNO-406;NS-187
Solubility≥51.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
Chemical Name(S)-N-(3-([4,5'-bipyrimidin]-2-ylamino)-4-methylphenyl)-4-((3-(dimethylamino)pyrrolidin-1-yl)methyl)-3-(trifluoromethyl)benzamide
SDFDownload SDF
Canonical SMILESCC1=CC=C(NC(C2=CC=C(CN3CC[C@H](N(C)C)C3)C(C(F)(F)F)=C2)=O)C=C1NC4=NC=CC(C5=CN=CN=C5)=N4
Shipping ConditionSmall Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

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Chemical structure

Bafetinib