Bafetinib
Catalog No.
BA2759
Bafetinib is an orally active tyrosine kinase inhibitor.
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Bafetinib is an orally active tyrosine kinase inhibitor.Bafetinib potentiates the activity of several pro-apoptotic homologous (BH)3-pure proteins (Bim, Bad, Bmf, and Bik) through the family-regulated intrinsic apoptotic pathway and induces apoptosis in Ph leukemia cells.Bafetinib has antitumor activity.
Physical Appearance | A solid |
Storage | -20°C |
M.Wt | 576.62 |
Cas No. | 859212-16-1 |
Formula | C30H31F3N8O |
Synonyms | INNO-406;NS-187 |
Solubility | ≥51.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O |
Chemical Name | (S)-N-(3-([4,5'-bipyrimidin]-2-ylamino)-4-methylphenyl)-4-((3-(dimethylamino)pyrrolidin-1-yl)methyl)-3-(trifluoromethyl)benzamide |
SDF | Download SDF |
Canonical SMILES | CC1=CC=C(NC(C2=CC=C(CN3CC[C@H](N(C)C)C3)C(C(F)(F)F)=C2)=O)C=C1NC4=NC=CC(C5=CN=CN=C5)=N4 |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
