Azaguanine-8
Catalog No.
B1667
Purine analogs
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Azaguanine-8 (CAS: 134-58-7) is a synthetic purine analog utilized in biomedical research due to its antineoplastic properties. Structurally similar to guanine, azaguanine-8 exerts its biological activity by competitively interfering with guanine metabolism, subsequently disrupting nucleic acid synthesis and cellular replication pathways. It demonstrates inhibitory effects on cell proliferation, making it a valuable tool in investigating nucleic acid metabolism and cancer biology in preclinical studies.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 152.11 |
| Cas No. | 134-58-7 |
| Formula | C4H4N6O |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥3.93 mg/mL in DMSO |
| Chemical Name | 5-amino-2,3-dihydrotriazolo[4,5-d]pyrimidin-7-one |
| SDF | Download SDF |
| Canonical SMILES | NC(N=C1NNN=C11)=NC1=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
