AU-15330
Catalog No.
BA4657
AU-15330 is a SWI/SNFATPase subunit and protein hydrolysis-targeted chimera (PROTAC) degrader.
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AU-15330 is a SWI/SNFATPase subunit and protein hydrolysis-targeted chimera (PROTAC) degrader.AU-15330 induces potent inhibition of tumor growth in a prostate cancer xenograft model and synergizes with enzalutamide, an AR antagonist.AU-15330 induces disease in a desmoplastic resistant prostate cancer (CRPC) model remission without toxicity.
| Physical Appearance | A solid |
| Storage | Tightly sealed and desiccated at 4°C |
| M.Wt | 755.93 |
| Cas No. | 2380274-50-8 |
| Formula | C39H49N9O5S |
| Chemical Name | (2S,4R)-1-((S)-2-(2-(4-(3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide |
| Canonical SMILES | OC1=C(C2=CC(N3CCN(CC(N[C@H](C(N4C[C@H](O)C[C@H]4C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)=O)C(C)(C)C)=O)CC3)=C(N)N=N2)C=CC=C1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
