ARV-393
Catalog No.
BA5849
ARV-393 is an orally effective, ubiquitin proteasome system-utilizing, targeted degradation.
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ARV-393 is an orally active, ubiquitin proteasome system-available, targeted degradation.ARV-393 consists of ligands coupled to target and E3 ligase, respectively.ARV-393 has DC and GI values <1nM in a variety of diffuse large B-cell lymphoma (DLBCL) and Burkitt's lymphoma (BL) cell lines.ARV-393 also exhibits considerable tumor suppressor activity in tumor xenograft model.ARV-393 is being used in studies to inhibit non-Hodgkin's lymphoma.
| Physical Appearance | A solid |
| Storage | 4°C, protect from light |
| M.Wt | 898.42 |
| Cas No. | 2851885-95-3 |
| Formula | C46H53ClFN9O7 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |