Artemisinine
Catalog No.
N1827
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Artemisinine (CAS: 63968-64-9) is a sesquiterpene lactone designed to modulate parasite cell integrity and cancer cell viability. Artemisinine exerts its biological activity primarily through interaction with parasite-derived heme groups, leading to the formation of reactive oxygen species that disrupt cell integrity, and by inducing oxidative stress and apoptotic pathways in tumor cells. In in vitro studies, Artemisinine demonstrates cytotoxicity toward cancer cells and antimalarial activity, with reported IC50 values ranging from 5 to 20 µM, depending on experimental conditions, cell, or parasite lines utilized. Based on these pharmacological properties, Artemisinine holds research potential in antimalarial and antitumor applications.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 282.33 |
| Cas No. | 63968-64-9 |
| Formula | C15H22O5 |
| Synonyms | Arteannuin |
| Solubility | insoluble in EtOH; insoluble in H2O; ≥13.7 mg/mL in DMSO |
| Chemical Name | (5aS,6R,8aS,9R,12S,12aR)-3,6,9-trimethyloctahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10(12H)-one |
| SDF | Download SDF |
| Canonical SMILES | C[C@H](CC[C@H]1[C@H]2C)[C@H](CC3)[C@@]11OOC3(C)O[C@H]1OC2=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
