Aristolochic Acid A
Catalog No.
N2032
A plant-derived compound that reduces AP-1 and NF-κB activity and BLCAP expression, commonly used to construct chronic kidney disease (aristolochic acid nephropathy) animal models.
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Aristolochic Acid A (CAS 313-67-7) is a plant-derived compound extracted from Aristolochia debilis that reduces AP-1 and NF-κB activity and BLCAP gene expression. The product should be sealed and stored in a cool, dry place.
Aristolochic Acid A is commonly used to establish chronic kidney disease (aristolochic acid nephropathy) animal models; administration induces tubulointerstitial damage and fibrosis.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 341.27 |
| Cas No. | 313-67-7 |
| Formula | C17H11NO7 |
| Synonyms | Aristolochic acid A |
| Solubility | insoluble in EtOH; insoluble in H2O; ≥17.05 mg/mL in DMSO with gentle warming and ultrasonic |
| Chemical Name | 8-methoxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid |
| Canonical SMILES | COc1cccc(c2c3c(C(O)=O)cc4c2OCO4)c1cc3[N+]([O-])=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
