Apocholic acid

Apocholic Acid is an endogenous bile acid that, as a natural product of cholesterol metabolism in the liver, plays a significant role in the bile acid metabolic network. Its molecular structure features a typical steroid skeleton, and through side chain modification, it forms a unique polar characteristic. After synthesis in the liver, it can be secreted into the intestine with bile, participating in the emulsification and absorption of lipid substances. As an endogenous metabolite, this compound not only participates in the regulation of the hepatointestinal circulation but also may regulate the expression of bile acid synthesis pathways and lipid metabolism-related genes by activating nuclear receptors such as the farnizol X receptor (FXR) and the progesterone X receptor (PXR).