Anti-ULK1 Rabbit Monoclonal Antibody
Catalog No.
MA5615
Anti-ULK1 Rabbit Monoclonal Antibody
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Act as a convergence point for multiple signals that control autophagy, and can bind to several autophagy-related (Atg) proteins, regulating phosphorylation states and protein trafficking. AMPK, activated during low nutrient conditions, directly phosphorylates ULK1 at multiple sites including Ser317, Ser555, and Ser777. Conversely, mTOR, which is a regulator of cell growth and an inhibitor of autophagy, phosphorylates ULK1 at Ser757 and disrupts the interaction between ULK1 and AMPK.
8408
ULK1; KIAA0722; Serine/threonine-protein kinase ULK1; Autophagy-related protein 1 homolog; ATG1; hATG1; Unc-51-like kinase 1
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 113 kDa; Observed MW: 120 kDa
Unmodified
IgG
Monoclonal Antibody
AP-7E3C6
Liquid
See label
Carrier Free
A synthesized peptide derived from human ULK1
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.