Anti-U1C Rabbit Monoclonal Antibody
Catalog No.
MA5585
Anti-U1C Rabbit Monoclonal Antibody
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Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
6631
U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C
Rabbit
Human, Rat
Unconjugated
Calculated MW: 17 kDa; Observed MW: 21 kDa
Unmodified
IgG
Monoclonal Antibody
AP-19E2A1
Liquid
See label
Carrier Not Free
A synthetic peptide of human U1-C
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-F, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.