Anti-Tuberin Rabbit Monoclonal Antibody
Catalog No.
MA5576
Anti-Tuberin Rabbit Monoclonal Antibody
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Tuberin is a product of the TSC2 tumor suppressor gene and an important regulator of cell proliferation and tumor development. Mutations in either TSC2 or the related TSC1 (hamartin) gene cause tuberous sclerosis complex (TSC), an autosomal dominant disorder characterized by development of multiple, widespread non-malignant tumors. Tuberin is directly phosphorylated at Thr1462 by Akt/PKB. Phosphorylation at Thr1462 and Tyr1571 regulates tuberin-hamartin complexes and tuberin activity.
7249
TSC2; Tuberous sclerosis 2 homolog protein; Tuberous sclerosis 2 protein; Tuberin; TSC4
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 201 kDa; Observed MW: 201 kDa
Unmodified
IgG
Monoclonal Antibody
AP-5F11D10
Liquid
See label
Carrier Free
A synthesized peptide derived from human Tuberin
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, FC
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.