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Anti-TROP2 Antibody (Datopotamab deruxtecan)

Catalog No.
F1364
Anti-TROP2 Antibody (Datopotamab deruxtecan)
Grouped product items
SizePriceStock Qty
100ug
$200.00
Ship with 3-5 days
1mg
$1,000.00
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Datopotamab (CDP7657) is a humanized anti-trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can be combined with the DNA topoisomerase I inhibitor Deruxtecan to generate an antibody-drug conjugate (ADC) Datopotamab deruxtecan. Datopotamab can be used in the study of triple-negative breast cancer and non-small cell lung cancer.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

149.3 kDa

Shipping

Dry ice

Cas No.

2238831-60-0

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

DS-1062a, MAAP-9001a, TINA1

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P09758

Reactivity

Human

Conjugation

Dxd

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

Immobilized rhTROP2(ECD)-chis at 2 μg/mL (30 μL/well) can bind Datopotamab-DXd (P100820D4.4) with the EC50 of 0.01250 μg/mL.

Target

TROP2

Note

Please avoid freeze-thaw cycles.