Anti-TP53BP2 Rabbit Monoclonal Antibody
Catalog No.
MA5471
Anti-TP53BP2 Rabbit Monoclonal Antibody
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Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
7159
53BP2; ASPP2; p53BP2; PPP1R13A; Tp53bp2
Rabbit
Human
Unconjugated
Calculated MW: 126 kDa; Observed MW: 150 kDa
Unmodified
IgG
Monoclonal Antibody
AP-3E11H5
Liquid
See label
Carrier Free
A synthesized peptide derived from human ASPP2
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.