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Anti-TNFSF7/CD27L/CD70 Antibody (Vorsetuzumab mafodotin)

Catalog No.
F1130
Anti-TNFSF7/CD27L/CD70 Antibody (Vorsetuzumab mafodotin)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Vorsetuzumab mafodotin (SGN-75) is an antibody-drug conjugate (ADC) consisting of a humanized monoclonal antibody directed against the extracellular domain of the human CD70 molecule and a cytotoxic tubulin polymerization inhibitor. It is used to treat renal cell carcinoma.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

146.1 kDa

Shipping

Dry ice

Cas No.

1165741-01-4

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

Vorsetuzumab mafodotin

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P32970

Reactivity

Human

Conjugation

MMAF

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Biological Activity

Immobilized humanCD70-His at 2 ug/mL (30 μL/well) can bind Anti-TNFSF7/CD27L/CD70 Antibody (Vorsetuzumab mafodotin) with the EC50 of 0.007612 ug/mL.

Target

TNFSF7 / CD27L / CD70

Note

Please avoid freeze-thaw cycles.