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Anti-TNFRSF5/CD40 Antibody (Mitazalimab)

Catalog No.
F1061
Anti-TNFRSF5/CD40 Antibody (Mitazalimab)
Grouped product items
SizePriceStock Qty
100ug
Please inquire
Ship with 3-5 days
1mg
Please inquire
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Mitazalimab (ADC-1013; JNJ-64457107) is an FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, such as dendritic cells (DCs), to prime tumor-reactive T cells. As a result, Mitazalimab induces tumor-specific T cell infiltration and tumor killing. Mitazalimab reshapes the tumor-infiltrating bone marrow microenvironment.

Quality Control

Quality Control & DataSheet

View current batch:
 

M.Wt

143.44 kDa

Shipping

Dry ice

Cas No.

2055640-86-1

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

ADC 1013, JNJ-64457107

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

P25942

Reactivity

Human

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Target

TNFRSF5 / CD40

Note

Please avoid freeze-thaw cycles.