Anti-Thrombomodulin Rabbit Monoclonal Antibody
Catalog No.
MA5412
Anti-Thrombomodulin Rabbit Monoclonal Antibody
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Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
7056
CD141; Fetomodulin; THBD; THRM; thrombomodulin; TM
Rabbit
Human
Unconjugated
Calculated MW: 60 kDa; Observed MW: 95 kDa
Unmodified
IgG
Monoclonal Antibody
AP-6G11B8
Liquid
See label
Carrier Not Free
A synthetic peptide of human Thrombomodulin
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.