Anti-SOCS1 Rabbit Polyclonal Antibody
Catalog No.
PA1340
Anti-SOCS1 Rabbit Polyclonal Antibody
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This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
8651
SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 24 kDa; Observed MW: 38 kDa
Unmodified
IgG
Polyclonal Antibody
Liquid
See label
Carrier Not Free
The antiserum was produced against synthesized peptide derived from human SOCS-1.
Affinity Purified
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
WB, IHC-F, IHC-P, ICC/IF, ELISA
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.