Toggle Nav
Close
  • Menu
  • Setting

Anti-SNAI1 Rabbit Polyclonal Antibody

Catalog No.
PA1339
Anti-SNAI1 Rabbit Polyclonal Antibody
Grouped product items
SizePriceStock Qty
50ul
$210.00
Ship with 3-5 days
100ul
$375.00
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells . Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines . In addition, Snail blocks the cell cycle and confers resistance to cell death . Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function .Tissue specificity: Expressed in a variety of tissues with the highest expression in kidney.

Quality Control

Quality Control & MSDS

View current batch:
 

Gene ID

6615

Alternative Names

SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna

Host

Rabbit

Reactivity

Human, Mouse

Conjugation

Unconjugated

M.Wt

Calculated MW: 29 kDa; Observed MW: 29 kDa

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Concentration

See label

Carrier

Carrier Not Free

Immunogen

The antiserum was produced against synthesized peptide derived from human SNAI1.

Purification

Affinity Purified

Buffer System

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application

WB, IHC-P, ICC/IF, ELISA

Shipping Condition

Blue ice

Storage

-20°C

Expiration Date

12 months

Note

Please avoid freeze-thaw cycles.