Anti-SHC Rabbit Monoclonal Antibody
Catalog No.
MA5106
Anti-SHC Rabbit Monoclonal Antibody
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Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals.
6464
SHC1; SHC; SHCA; SHC-transforming protein 1; SHC-transforming protein 3; SHC-transforming protein A; Src homology 2 domain-containing-transforming protein C1; SH2 domain protein C1
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 63 kDa; Observed MW: 46, 52, 66 kDa
Unmodified
IgG
Monoclonal Antibody
AP-4E4A10
Liquid
See label
Carrier Free
A synthesized peptide derived from human SHC
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.