Anti-RYK Rabbit Monoclonal Antibody
Catalog No.
MA4994
Anti-RYK Rabbit Monoclonal Antibody
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May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
6259
ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik
Rabbit
Human
Unconjugated
Calculated MW: 68 kDa; Observed MW: 72 kDa
Unmodified
IgG
Monoclonal Antibody
AP-15B1G2
Liquid
See label
Carrier Not Free
A synthetic peptide of human RYK
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-F, IHC-P, ICC/IF, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.