Anti-RAGE Rabbit Monoclonal Antibody
Catalog No.
MA4858
Anti-RAGE Rabbit Monoclonal Antibody
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The receptor for advanced glycation end products (RAGE) is member of the immunoglobulin (Ig) superfamily. Mediates interactions of advanced glycosylation end products (AGE). Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase, which leads to activation of transcription.
177
AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products
Rabbit
Mouse
Unconjugated
Calculated MW: 43 kDa; Observed MW: 55 kDa
Unmodified
IgG
Monoclonal Antibody
AP-9B5G7
Liquid
See label
Carrier Not Free
A synthetic peptide of human RAGE
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.