Anti-RAGE Rabbit Monoclonal Antibody
Catalog No.
MA4859
Anti-RAGE Rabbit Monoclonal Antibody
Featured Products
The receptor for advanced glycation end products (RAGE) is member of the immunoglobulin (Ig) superfamily. Mediates interactions of advanced glycosylation end products (AGE). Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase, which leads to activation of transcription.
177
AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 43 kDa
Unmodified
IgG
Monoclonal Antibody
AP-18A3D11
Liquid
See label
Carrier Free
A synthesized peptide derived from human RAGE
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.