Anti-Rad21 Rabbit Monoclonal Antibody
Catalog No.
MA4844
Anti-Rad21 Rabbit Monoclonal Antibody
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Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.
5885
RAD21; HR21; KIAA0078; NXP1; Double-strand-break repair protein rad21 homolog; hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog
Rabbit
Human, Hamster
Unconjugated
Calculated MW: 72 kDa; Observed MW: 130 kDa
Unmodified
IgG
Monoclonal Antibody
AP-20D7C9
Liquid
See label
Carrier Not Free
A synthetic peptide of human Rad21
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-F, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.