Anti-Rad21 Rabbit Monoclonal Antibody
Catalog No.
MA4845
Anti-Rad21 Rabbit Monoclonal Antibody
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Rad21 is one of the major cohesin subunits that holds sister chromatids together until anaphase, when proteolytic cleavage by separase, a caspaselike enzyme, allows chromosomal separation. Rad21 interacts with Rec8 to form a cohesin complex that functions in sister chromatid alignment. Rad21 is also involved in the repair of double-strand breaks in DNA and is essential for mitotic growth. Rad21 undergoes a C-terminal cleavage induced by diverse stimuli right before apoptosis.
5885
RAD21; HR21; KIAA0078; NXP1; Double-strand-break repair protein rad21 homolog; hHR21; Nuclear matrix protein 1; NXP-1; SCC1 homolog
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 72 kDa; Observed MW: 72,128 kDa
Unmodified
IgG
Monoclonal Antibody
AP-10B10E4
Liquid
See label
Carrier Free
A synthesized peptide derived from human Rad21
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, FC
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.